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Hybrid CPU+GPU

Best variant: Q5_K_M

CPU + GPU hybrid — not enough VRAM (6 GB < 52 GB min), but 64 GB RAM is sufficient. Expect significantly slower inference.

GPU VRAM
6 GB
Min VRAM (best fit)
52 GB
Recommended VRAM
58 GB
Estimated tok/s
~1

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Every Qwen 2.5 72B quantization on NVIDIA GeForce GTX 1060 6GB

Each row runs the compatibility engine against your VRAM, RAM, and the model's requirements.

QuantizationFile SizeMin VRAMRec VRAMContextVerdictEstimated tok/s
Q2_K27 GB29 GB36 GB8K / 128KHybrid CPU+GPU~2
Q3_K_M35 GB37 GB44 GB8K / 128KHybrid CPU+GPU~1
Q4_K_M42 GB44 GB48 GB8K / 128KHybrid CPU+GPU~1
Q5_K_MBest fit50 GB52 GB58 GB8K / 128KHybrid CPU+GPU~1

Upgrade options that fit Qwen 2.5 72B better

Cheapest fit

Apple M1 Max

64 GB VRAM · ~7 tok/s

Best value

Apple M1 Ultra

128 GB VRAM · ~13.9 tok/s

Best performance

Apple M4 Ultra

256 GB VRAM · ~19 tok/s

Rent GPU instead of buying one

If local fit is weak, cloud GPU gets you running today without hardware upgrade.

All hardware for Qwen 2.5 72BBest GPU for Qwen 2.5 72BModels that fit NVIDIA GeForce GTX 1060 6GBFull model detailsBrowse all models